When USG Ishimura, a huge mining ship, comes in contact with a mysterious extraterrestrial artifact in a distant star system, all communication with Earth is broken. Engineer Isaac Clarke is sent to the spaceship on a mission to repair Ishimuras communication system, but when he arrives he is met by a living nightmare - the spaceship is a hovering scene of an indescribable massacre, where the crew has been maimed and infected by an ancient alien torment. Clarkes repair missions turn into a battle for survival, but he fights not only to save himself but also to return the ancient artifact to the planet where it belongs ... at any cost. Welcome to the darkest depths of Dead Space ...